Dr. Vince Clinical Research Brochure

YOUR

FULL

SERVICE

CRO™

+1 913-333-3000

DrVinceCRO.com

2 Your Full-Service CRO

Areas of Expertise

Dr. Vince Clinical Research (DVCR) is a full-service CRO specializing in Phase I-II clinical trials across various

designs, therapeutic areas and drug classes. Studies are performed at our world-class Phase I research

facility or through strategic partnerships with qualified external sites where DVCR serves as the CRO.

Therapeutic Areas

CNS, Psychiatry

& Neuology

Addiction &

Substance Use

Disorders

Allergy &

Immunology

Cardiometabolic

& Obesity

Pain

Respiratory

Dermatology

Infectious

Diseases

First-in-Human

SAD/MAD

DDI

TQT/Early QT

PK/PD

Food Effect

Proof-of-

Concept

BA/BE

Hepatic

Impairment

Renal

Impairment

Study Types

Human Abuse

Potential

Patient

Studies

Multi-Site

Phase 1b/2

Your Full-Service CRO 3

Full-Service CRO Solutions

Support Services

for Phase I-II Clinical Trials

Data

Management

Biostatistics

& Programming

Phase I-II

Multi-Site

Trials

Project

Management

Clinical

Monitoring

Medical

Writing

PK/PD

Analysis &

Modeling

Medical

Monitoring

100-Bed

Phase I Unit

Central

Laboratory

Services

4 Your Full-Service CRO

Phase I-II Multi-Site Trials

By combining our full suite of CRO support services and a network of strategic site partners globally, we manage

complex multi-site trials in patients and healthy normal volunteers across a diverse range of therapeutic areas

and trial designs.

Our Model

We prioritize sites that align with our principles to help our sponsors reach their milestones faster.

Quality sites are imperative for a

successful trial.

Sites require expedited

payments to avoid study delays.

This reinforces our collaborative,

true partnership approach.

Site ID and Selection

Prioritizing Site Payments

Site Engagement

We provide sites with essential

tools, support and communication.

Central Laboratory Services

Customizable Kits

Rapid Turnaround

Real-Time Sample Stability

Flexible Team

Emergency Testing

Comprehensive Oversight

Florence Trial

Operations Platform

The Florence Trial Operations Platform accelerates the study

startup and enables seamless document distribution, tracking

and remote monitoring across our sites. It provides real-time

visibility and quality control, eliminating the need for back-and-

forth exchanges and integrates directly with Trial Master Files

(TMFs) for efficient filing and document updates. Whether sites

use a Florence account or paper ISF, this tool keeps DVCR

connected and informed—especially during critical phases such

as startup and site activation.

Your Full-Service CRO 5

The DVCR Difference

Every single detail of our organization was built to deliver speed and quality. Our highly experienced clinical team

consistently meets recruitment goals and achieves key milestones for our sponsors.

Team Continuity

Maintining key leadership

throughout every study

Flexible Partner

Physician led and adapting to your

needs at every stage

Technology & Innovation

A leader in technology-powered

clinical research

Rapid Response Time

Delivering rapid communication and

exceptional customer service

6 Your Full-Service CRO

Luxurious Phase I Unit

Designed Differently

We operate one of the world’s most innovative and technologically advanced research centers, purpose-built

to support speed, efficiency and high-quality data. Our facilities provide an ideal environment for seamless

study execution.

75,000 square foot research complex

100-bed clinical pharmacology unit

cGMP compliant pharmacy

Market leading technology for cardiac telemetry

State-of-the-art clinical laboratory

Surgical suite for advanced procedures

Your Full-Service CRO 7

Our pharmacy team has over 50 years of combined experience in early phase clinical research, with

expertise in the handling and preparation of investigational products across various routes of administration.

cGMP Compliant Pharmacy

Located within our Phase I unit, the 2,500 square foot cGMP compliant compounding pharmacy contains five

distinct areas for the preparation and storage of investigational products:

Main pharmacy area with closed cell insulation

for maintaining environmental controls for

ambient storage of investigational products

Controlled substance licensing for Schedules I-V

USP 795 compliant negative pressure

extemporaneous preparation room

USP 797 compliant ISO 8 (Class 100,000)

anteroom

USP 797 compliant ISO 7 (Class 10,000) clean

room

Spacious storage area with cold storage units

Pharmacy Features

and Equipment

Thermo Fisher cold storage units with

24/7/365 temperature monitoring

Secured storage of controlled substances

Class II, Type A2 biological safety cabinets

Semi-micro analytical balance for

weighing API powder

Independent narrow spectrum

570nm amber LED lights for handling

photosensitive API

Labconco XPert Filtered Balance System

HEPA filtration throughout entire pharmacy

Biometric facial screening

8 Your Full-Service CRO

At DVCR, a significant component of being designed differently is how much we value the volunteer experience.

This enables us to achieve unmatched speed and diversity in recruitment. You can see this sentiment at work

the second you walk through our doors. Additionally, the entire DVCR campus features an array of volunteer

amenities, each one thoughtfully planned to enhance the volunteer experience in order to optimize recruitment

and retention.

Sports-themed dining

room with plush seating

and nine large-screen TVs

Gaming room

equipped with state-of-

the-art systems

VIP lounge with floor-

to-ceiling windows

and spacious seating

Committed to

enhancing the

volunteer experience

Unsurpassed Recruitment

and Retention

Your Full-Service CRO 9

Expert Insight and Support

At DVCR we have one of the most experienced

research teams in the country.

At DVCR, we invest in people, cultivating unmatched expert insight and support. Each member of our

diverse research team was hand-selected to provide expertise and practical insights into every facet of

study execution.

Robust training

Cutting-edge

technology

Positive and

uplifting work

culture

A workplace

designed around

collaboration

10 Your Full-Service CRO

Integration From

Start to Finish

Utilizing cloud-based technology and the

highest levels of encryption available, we

provide secure data with optimal redundancy,

reliability and accessibility.

Technology Powered

Clinical Research

Clinspark eSource/EDC and Clinic

Workflow Automation System

Florence electronic Investigator Site File/eTMF

Wireless Temperature Monitoring

Touchless Biometric Access Controls

Wifi-Telemetry with Redundant Server Storage

By using these and other automated systems,

we have transformed standard industry

practices to become a leader in technology-

based clinical research.

Medidata CTMS

Your Full-Service CRO 11

Smarter Faster Data®

We define Smarter Faster Data® as accurate, actionable and audit-ready. This accelerates your time in the clinic

and speeds up review, quickly producing clean and robust data through seamless tech integration.

Expedited IRB review via

our collaboration with

WCG IRB

Strategic partnership

with Clario to deliver

high-quality cardiac

safety data

Dedicated vital signs

machines at each bed to

reduce data variability

Equipment integration

with eSource/EDC for

automatic data upload

Deployment of bar code

scanning for improved

data quality and subject

verification

Real-time Sponsor

access to live data

12 Your Full-Service CRO

In-House Clinical Laboratory

Our state-of-the-art clinical laboratory enhances the capabilities of our clinical pharmacology unit by

enabling in-house safety testing, minimizing logistical challenges and enabling us to deliver faster results.

Our clinical laboratory performs a comprehensive range of safety tests including:

Chemistry and

Immunoassay

Hematology

CBC with 5-Part

Differential

Coagulation

Urinalysis with

Microscopy

Key Features of Our Clinical Lab

Advanced

instrumentation with

high throughput and

comprehensive

test menus

Duplicate

instrumentation for

continuous operation,

eliminating downtime

Full integration with

Our clinic eSource/EDC

system for enhanced

speed and accuracy

Your Full-Service CRO 13

14 Your Full-Service CRO

7401 West 91st Street,

Overland Park, KS, USA 66212

ADDRESS

+1 913-333-3000

info@drvince.com

PHONE & EMAIL

DrVinceCRO.com

linkedin.com/company/dvcr

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